High dose vs low dose Testosterone replacement

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Swim_1650
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High dose vs low dose Testosterone replacement

Post by Swim_1650 »

I’m curious for those on T post castration how testosterone replacement compared to your natural T levels. I suppose injection vs topical would also affect things. For those who felt different, how so?

I’m also interested in anyone who has taken low dose testosterone. What was your goal T blood levels? How did this compare to your “normal” levels. What effects did you get from the T, what symptoms of low T did you have. Where was your libido, ability to have an erection, weight gain/muscle loss, mood, energy, etc?

Thanks!
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WheelyFixed
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Re: High dose vs low dose Testosterone replacement

Post by WheelyFixed »

I don't know that there is a lot comparing high and low dose T. I know that many have said that injections tended to give a 'roller coaster' effect, as the level peaked right after and then dropped over time until the next shot. As you'd expect, the longer the spacing between shots the more pronounced the effect was, so many tried to get smaller shots more often to reduce it. OTOH topical is usually applied daily, so you get a more level state.

For what it's worth, after I got hurt I read that T levels often dropped and this could contribute to bone loss issues, so I had it checked and found it was about 50% of 'normal' for my age. I then used topical to get me back to 'normal' for several years before I learned about the option to become a eunuch.

The first thing the TG doc had me do was stop the topical which dropped me back to half normal. I then started chemical castration w/ Lupron and after the first month added E patches. My levels went to 'undetectable' and haven''t had a detectable level since, which somewhat concerned me. I wanted to try Deca-Durabolin (sp?) as I have read that it is supposed to do a better job for bone density, muscle mass, etc. without the other effects of T, but it is apparently not available in the US. So I'm now trying one pump of 12.5mg T topical every other day to see if I can get my level UP to 'castrate' level while continuing to use the E patches.... Not sure what my current levels are as they haven't been tested since I started doing this.

I seem to be getting a little faster regrowth of pubic hair :x and I seem to be doing a little bit better on strength, but I haven't noticed a lot of other changes since I've started this.

WheelyFixed
Paraplegic - T-5, ASIA-B. 2010 Injury left non-functional & frustrated. 4/24/22, stop T. 5/4 start 3.75mg Lupron. 6/29 - T ~0. 7/7 - start E. 9/2 stop Lupron. 3/30/23 - GOT LETTERS! surgery (O&S) 9/28/23. Doing 0.75mg/day E patch as HRT
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Re: High dose vs low dose Testosterone replacement

Post by sftineun »

WheelyFixed wrote: Wed May 13, 2026 2:21 am I don't know that there is a lot comparing high and low dose T. I know that many have said that injections tended to give a 'roller coaster' effect, as the level peaked right after and then dropped over time until the next shot. As you'd expect, the longer the spacing between shots the more pronounced the effect was, so many tried to get smaller shots more often to reduce it. OTOH topical is usually applied daily, so you get a more level state.

For what it's worth, after I got hurt I read that T levels often dropped and this could contribute to bone loss issues, so I had it checked and found it was about 50% of 'normal' for my age. I then used topical to get me back to 'normal' for several years before I learned about the option to become a eunuch.

The first thing the TG doc had me do was stop the topical which dropped me back to half normal. I then started chemical castration w/ Lupron and after the first month added E patches. My levels went to 'undetectable' and haven''t had a detectable level since, which somewhat concerned me. I wanted to try Deca-Durabolin (sp?) as I have read that it is supposed to do a better job for bone density, muscle mass, etc. without the other effects of T, but it is apparently not available in the US. So I'm now trying one pump of 12.5mg T topical every other day to see if I can get my level UP to 'castrate' level while continuing to use the E patches.... Not sure what my current levels are as they haven't been tested since I started doing this.

I seem to be getting a little faster regrowth of pubic hair :x and I seem to be doing a little bit better on strength, but I haven't noticed a lot of other changes since I've started this.

WheelyFixed
I thought the e-patch is supposed to be more effective than any T because the body converts the T to E for bone health. However, of course, T is important for muscle mass and other health benefits, but it also comes with the very effects we wanted to get rid of when we decided to get castrated.
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Re: High dose vs low dose Testosterone replacement

Post by WheelyFixed »

I agree, but I've been having problems w/ muscle mass / strength for doing critical things like transfers and so on, and am hoping that the very low dose T will help with that part without being enough to bring back the libido / desires that i got fixed to get rid of...

Per the Eunuch Friends Wiki article https://eunuchfriends.miraheze.org/wiki/Deca_Durabolin it sounds like Deca Durabolin / Nandrolone would have been the ideal approach as it checks off ALL boxes for the benefits I'd like to get without the undesired 'androgenic effects' that come with replacing T, and that arguably one doesn't really get from Estrogen.

I've also looked it up on other reputable medical sites and found similar descriptions about what it did, w/o the references to eunuchs, so I feel it's pretty accurate.

Unfortunately according to my TG doc she can't find ANY source for it in the US, checking all the 'formularies' that she has access to (given her association with MGH, I'd expect that list to be about as good as one can get...) :cry: She said that unless I could find an overseas source or a compounding pharmacy that would make it, neither of which she could write prescriptions for or officially record that I was using (so no insurance coverage) there was no way I could get it... The low dose T experiment I'm doing now is the best alternative she could offer me...

WheelyFixed
Paraplegic - T-5, ASIA-B. 2010 Injury left non-functional & frustrated. 4/24/22, stop T. 5/4 start 3.75mg Lupron. 6/29 - T ~0. 7/7 - start E. 9/2 stop Lupron. 3/30/23 - GOT LETTERS! surgery (O&S) 9/28/23. Doing 0.75mg/day E patch as HRT
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Re: High dose vs low dose Testosterone replacement

Post by eggless splitty »

I believe now, that the dosis will not be so deciding. here my last experiences:
Since years i lotion and massage each morning a 2/3 baggy of testo-gel onto my flat baggy and the limp twins. Its very nice prickling and bloodfilling and the best start into the day together with my first coffee. My wife still is sleeping in the upper room. And so - beeing allone - i can also in a good way milk of my twins sometimes. Normally its not so easy anymore and will take time and additionally some prostate pressure to reach it finally.
And so over the whole winter i have not so much milked off my twins, perhaps only one until two times in a month. And if i got it, then i was usually weakly and beat for the whole day!
Last Sunday morning suddenly - always after the same dosis testo - i got lust for an milking off and reached the orgasm in a right quickly and easily way, without to feel a great weakness over the following day. As like in younger years, haha!
And now, at Tuesday - i had already again a great urg to jerk and milk me off! And i tried it, with some rubber band around my stuffs root - and i got it still quicker then at Sunday morning. And so easily, withoud any backwards support! Only laying in the settle and stretching my body hard in length and ramrod.
In three days two splashings - how that? Its the spring, the sun, which will bring our body in sway? Will my usually low blood pressure raise in Spring?
without any changing of my testo-dosis! I take only a 2/3 baggy, because i will save some baggies, which i will send to a chat friend, who will be gelded also, because his dead eggs are shrivled and vanished totally. But because he will have a Mea, he is ashamed to go to the Uro. Indeed he will go down without testo and his dick is shrivled already a good part!! And therewhy i will try to help him atleast with one nice filled letter in a quarter...
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